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| Brain stroke treatment |
Created an effective tool for the treatment of stroke
Employees of hospitals in the West Toronto (Toronto Western Hospital) in Ontario reported the successful testing of new drugs for the treatment of stroke.
If the vehicle taken within three hours after stroke onset, the brain damage can be minimized, says New Scientist.
Stroke - a strong violation of blood circulation in the brain. If the patient does not help within 24 hours, then all can be fatal. With a lack of oxygen and nutrients to the brain tissue dies. Currently there is only one approved means of treatment - tissue plasminogen activator (present in the body protein capable of forming blood clots break). It is most effective if applied within a half hours after stroke onset, but, unfortunately, not always available. Therefore, experts for a long time developing drugs that will work after 2 or more hours after its occurrence.
During the experiments, Michael Timianski and colleagues simulated the consequences of stroke in monkeys receiving up to PSD-95 inhibitor or placebo. According to experts, PSD-95 inhibitors interfere with the process that causes cell death when the brain is deprived of oxygen. To test their effectiveness, they used MRI to calculate the volume of brain damage within 30 days after treatment. In addition, experts also conducted behavioral tests at specific intervals during the same period.
Employees of hospitals in the West Toronto (Toronto Western Hospital) in Ontario reported the successful testing of new drugs for the treatment of stroke.
If the vehicle taken within three hours after stroke onset, the brain damage can be minimized, says New Scientist.
Stroke - a strong violation of blood circulation in the brain. If the patient does not help within 24 hours, then all can be fatal. With a lack of oxygen and nutrients to the brain tissue dies. Currently there is only one approved means of treatment - tissue plasminogen activator (present in the body protein capable of forming blood clots break). It is most effective if applied within a half hours after stroke onset, but, unfortunately, not always available. Therefore, experts for a long time developing drugs that will work after 2 or more hours after its occurrence.
During the experiments, Michael Timianski and colleagues simulated the consequences of stroke in monkeys receiving up to PSD-95 inhibitor or placebo. According to experts, PSD-95 inhibitors interfere with the process that causes cell death when the brain is deprived of oxygen. To test their effectiveness, they used MRI to calculate the volume of brain damage within 30 days after treatment. In addition, experts also conducted behavioral tests at specific intervals during the same period.
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